Iko Kushungurudza Kubata KweMuviri Homeostasis

ziviso

Munhu wese anobata nazvo kushushikana pane imwe nguva muhupenyu hwavo. Kungave kubvunzurudzwa kwebasa, zuva rekupedzisira rakakura, chirongwa, kana bvunzo, kushushikana kuripo kuchengetedza muviri uchishanda mune yega yega mamiriro ari kufamba nemuviri. Kushungurudzika kunogona kubatsira kugadzirisa muviri rokuzvidzivirira uye kubatsira metabolize homeostasis sezvo muviri unowedzera simba rawo zuva rose. Pakubata ne kusingaperi kunetseka inogona kukonzera kusagadzikana kwemetabolism mumuviri senge kusagadzikana kweura, kuzvimba, uye kuwedzera kwemazinga eglucose eropa. Kushungurudzika kwenguva refu kunogonawo kukanganisa mafungiro uye hutano hwemunhu, madyiro, uye kunaka kwekurara. Chinyorwa chanhasi chichatarisa kana kushushikana kuri chinhu chakanaka kana chakaipa, kuti kunobata sei muviri, uye mhedzisiro yezvinoitwa nekusingaperi kusagadzikana kumuviri. Endesa varwere kune vane certified, vane hunyanzvi vanopa vanorapa ura kune vanhu vanotambura autonomic neuropathy. Isu tinotungamira varwere vedu nekutaura kune vatinoshanda navo vekurapa zvinoenderana nekuongorora kwavo kana zvakakodzera. Isu tinoona kuti dzidzo yakakosha pakubvunza mibvunzo ine njere kune vatinopa. Dr. Alex Jimenez DC anopa ruzivo urwu sebasa rekudzidzisa chete. Disclaimer

 

Inishuwarenzi yangu inogona kuibhadhara here? Hongu, zvingadaro. Kana iwe usina chokwadi, heino chinongedzo kune vese vanopa inishuwarenzi vatinovhara. Kana uine chero mibvunzo kana zvinokunetsa, ndapota fonera Dr. Jimenez pa915-850-0900

Kuita Stress Kwakanaka Here Kana Kuti Kwakaipa?

 

Unonzwa uchifunganya nguva dzose here? Zvakadini nekunzwa musoro unogara uchinetsa? Kunzwa kuremerwa uye kurasikirwa nekutarisa kana kukurudzira? Zvose izvi zviratidzo zvinhu zvinoshungurudza izvo munhu ari kusangana nazvo. Zvidzidzo zvekutsvakurudza zvakatsanangura kushushikana kana cortisol sehomoni yemuviri inopa zvakasiyana siyana pamabasa akasiyana muhurongwa hwega hwega. Cortisol ndiyo yekutanga glucocorticoid iyo inobva kune adrenal cortex. Panguva imwecheteyo, iyo HPA (hypothalamus-pituitary-adrenal) axis inobatsira kugadzirisa kugadzirwa uye kuvharirwa kwehomoni iyi kune yese yemuviri. Iye zvino cortisol inogona kubatsira uye kukuvadza muviri, zvichienderana nemamiriro ezvinhu ari munhu. Zvimwe zvidzidzo zvetsvakurudzo zvakataurwa kuti cortisol inotanga uye inokanganisa huropi nemuviri wese sezvo kushushikana muchimiro chayo chakanyanya kunogona kukonzera kuti muviri ugadzirise uye urarame. Mhinduro dzakaoma kubva kucortisol dzinobvumira neural, moyo, immune, uye metabolic basa mumuviri. 

 

Inobata Sei Muviri weMetabolism?

Ikozvino cortisol inokanganisa metabolism yemuviri kana ichidzorwa mukutenderera kunononoka, kwakadzikama kunoderedza corticotropin-releasing hormone (CRH) uye inowedzera kukura kwehomoni (GH). Zvidzidzo zvekutsvaga zvakaratidza kuti kana adrenal glands ichibudisa cortisol, inotanga kuva nekubatana kwakaoma ne hypothalamus uye pituitary glands munheyo uye endocrine systems. Izvi zvinokonzeresa kuti adrenal uye thyroid basa mumuviri ribatanidzwe zvakanyanya apo iri pasi pekutonga kwe hypothalamus uye tropic mahormone. Iyo thyroid inokwikwidza neadrenal nhengo ye tyrosine. Zvidzidzo zvekutsvaga zvakawana kuti tyrosine inoshandiswa kugadzira cortisol pasi pekunetsekana uku ichidzivirira cognitive basa kuderera kunoteerera kushushikana kwemuviri. Nekudaro, kana muviri ukatadza kuburitsa yakakwana tyrosine, inogona kukonzera hypothyroidism uye kuita kuti cortisol hormone ive isingaperi.

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Muchidimbu Pamusoro Pekushushikana-Vhidhiyo

Wakambonzwa kurwadziwa nemusoro kunongoerekana kwaitika pasina kwaunobva? Wagara uchiwedzera uremu kana kupera uremu here? Iwe unonzwa uchinetseka kana kushushikana nguva dzose kuti zviri kukanganisa kurara kwako here? Izvi zvese zviratidzo uye zviratidzo zvemazinga ako ecortisol achishanduka kuita chimiro chavo chisingaperi. Vhidhiyo iri pamusoro inoratidza zvinoita kushushikana kumuviri wako uye kuti zvinogona kukonzera zviratidzo zvisingadiwe. Kana paine kushushikana kusingaperi mumuviri, iyo HPA axis (neuro-endocrine) haina kuenzana nekuda kwekushushikana-kwepakati activators zvinosanganisira autoimmune thyroid chirwere (AITD). Kana paine kushushikana kusingaperi mumuviri, zvinogona kukonzera kugadzirwa kwakanyanya kwemakomisheni ekuzvimba mumuviri anogona kugadzira IR. Izvo zvinopisa zvinhu zvinogona kukuvadza kana kusaita insulin receptors inotungamira kune insulin kuramba. Izvi zvinobva zvabatsira pakuparara kwechimwe kana zvimwe zvinhu zvinodiwa kuti upedze hurongwa hwekutakura glucose mumuviri.

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Mhedzisiro yeChisingaperi Cortisol Mumuviri

 

Kana paine kusagadzikana kusingaperi mumuviri uye kusati kwarapwa kana kuderedzwa pakarepo, zvinogona kutungamirira kune chimwe chinhu chinonzi allostatic load. Allostatic mutoro unotsanangurwa sekupfeka uye kubvaruka kwemuviri nehuropi nekuda kwekusagadzikana kusingaperi kana kusashanda kwemasisitimu emuviri anowanzo kubatanidzwa mumatambudziko ezvakatipoteredza uye kugadzirisa. Zvidzidzo zvekutsvaga zvakaratidza iyo allostatic load inokonzera kuwanda kwekuvanzika kwemahomoni senge cortisol uye catecholamine kupindura kune zvisingaperi zvinoshungurudza zvinokanganisa muviri. Izvi zvinoita kuti HPA axis iite chimwe chezvinhu zviviri: kushanda zvakanyanya kana kutadza kuvhara mushure mezviitiko zvinoshungurudza zvichikonzera kukanganisa kurara. Dzimwe nyaya dzinoitwa nekusingaperi kusagadzikana kumuviri dzinogona kusanganisira:

• Kuwedzera insulin secretion uye mafuta deposition
• Yakashandurwa immune function
• Hypothyroidism (adrenal kuneta)
• Sodium nemvura kuchengetedza
• Kurasika kwekurara kweREM
• Kusagadzikana mupfungwa uye mupfungwa
• Kuwedzera kwemoyo wengozi zvinhu

Zviratidzo izvi zvinoita kuti muviri usashande, uye tsvakurudzo zvidzidzo zvakaratidza kuti zvinonetsa zvakasiyana-siyana zvinogona kukuvadza muviri. Izvi zvinogona kuita kuti zviome zvakanyanya kuti munhu agone kurarama nekushushikana uye kuzvideredza.

mhedziso

Pakazara, kushushikana kana cortisol ihomoni iyo muviri inoda kushanda nemazvo. Kusagadzikana kwepfungwa mumuviri kubva kune kwakasiyana siyana zvinonetsa kunogona kukonzera akawanda metabolic dysfunctions senge hypothyroidism, kuwedzera huremu, insulin kuramba, uye metabolic syndrome, kutaura zvishoma. Kusagadzikana kwepfungwa kunogonawo kukonzera kusagadzikana kwekurara sezvo HPA axis yakasungirirwa kumusoro uye inogona kuita sekudzikamisa zvishoma. Kana vanhu vatanga kuwana nzira dzekubata neaya akasiyana zvinonetsa, vanogona kuderedza kushushikana kwavo kudzoreredza kune zvakajairika uye kusanetsekana.

 

References

Jones, Carol, naChristopher Gwenin. "Cortisol Level Dysregulation uye Kuwandisa Kwayo-Ndiyo Chisikwa Alarm Clock?" Physiological Reports, John Wiley and Sons Inc., Ndira 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC7749606/.

McEwen, Bruce S. "Mitemo Yepakati Yekushungurudzika Mahomoni Muhutano uye Chirwere: Kunzwisisa Dziviriro uye Inokuvadza Migumisiro Yekushungurudzika uye Kushushikana Kwepfungwa." European Journal of Pharmacology, US National Raibhurari yeMishonga, 7 Kubvumbi 2008, www.ncbi.nlm.nih.gov/pmc/articles/PMC2474765/.

McEwen, Bruce S. "Kushushikana kana Kushushikana: Chii Chinosiyana?" Zvinyorwa zvePsychiatry & Neuroscience: JPN, US National Raibhurari yeMishonga, Gunyana 2005, www.ncbi.nlm.nih.gov/pmc/articles/PMC1197275/.

Rodriquez, Erik J, nevamwe. "Allostatic Load: Kukosha, Zvicherechedzo, uye Zvibodzwa Sarudzo muVashoma uye Nekusiyana Kwevanhu." Chinyorwa cheUrban Health: Bulletin yeNew York Academy yeMishonga, Springer US, Kurume 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6430278/.

Thau, Lauren, nevamwe. "Physiology, Cortisol - Statpearls - NCBI Booksherufu." Mu: StatPearls [Internet]. Treasure Island (FL), StatPearls Publishing, 6 Sept. 2021, www.yori.nlm.nih.gov/books/NBK538239/.

Mudiki, Simon N. "L-Tyrosine Kuderedza Migumisiro Yekushushikana?" Zvinyorwa zvePsychiatry & Neuroscience: JPN, US National Raibhurari yeMishonga, Chivabvu 2007, www.ncbi.nlm.nih.gov/pmc/articles/PMC1863555/.

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