Diki Fiber Neuropathy: Zvaunoda Kuziva

Vanhu vanoonekwa vaine peripheral neuropathy, kana nediki fiber neuropathy, vanogona kunzwisisa zviratidzo uye zvinokonzeresa rubatsiro neangangove marapirwo?

Diki Fiber Neuropathy

Diki fiber neuropathy imhando chaiyo yeuropathy, sezvo kune marudzi akasiyana, ari kukuvara kwetsinga, kukuvara, chirwere, uye / kana kusashanda. Zviratidzo zvinogona kukonzera kurwadziwa, kurasikirwa kwekunzwa, uye zviratidzo zvekugaya uye weti. Zviitiko zvakawanda zveuropathy senge peripheral neuropathy zvinosanganisira madiki uye makuru fiber. Zvikonzero zvinowanzoitika zvinosanganisira chirwere cheshuga chenguva refu, kushomeka kwekudya, kunwa doro, uye chemotherapy.

• Diki fiber neuropathy inoonekwa mushure mekuongororwa kwekuongorora kunoratidza zviri pachena kuti diki tsinga fibers inobatanidzwa.
• Iwo madiki tsinga fiber anoona kunzwa, tembiricha, uye kurwadziwa uye anobatsira kudzora mabasa asingadi.
• Isolated diki-fiber neuropathy haiwanzo, asi tsvakiridzo irikuenderera mberi parudzi rwekukuvara kwetsinga uye kurapwa kunokwanisa. (Stephen A. Johnson, nevamwe, 2021)
• Diki fiber neuropathy haina njodzi chaiyo asi chiratidzo/chiratidzo chechikonzero chechikonzero/mamiriro ari kukanganisa tsinga dzemuviri.

zviratidzo

Zviratidzo zvinosanganisira: (Heidrun H. Krämer, nevamwe, 2023)

• Marwadzo - zviratidzo zvinogona kubva kune zvinyoro kana zvine mwero kusagadzikana kusvika pakushungurudzika kwakanyanya uye zvinogona kuitika chero nguva.
• Kurasikirwa kwekunzwa.
• Nekuti tsinga diki dzinobatsira nekugaya, BP, uye kudzora dundira - zviratidzo zve autonomic dysfunction zvinogona kusiyana uye zvinogona kusanganisira:
• Kuvhara, manyoka, kusagadzikana, kuchengetedza weti - kusakwanisa kubvisa zvachose dundira.
• Kana paine kufambira mberi kwekukuvara kwetsinga, kusimba kwemarwadzo kunogona kuderera, asi kurasikirwa kwekunzwa kwakajairwa uye zviratidzo zvekuzvimirira zvinogona kuwedzera. (Josef Finsterer, Fulvio A. Scorza. 2022)
• Hypersensitivity kunobata uye kunzwa kurwadziwa kunogona kukonzera marwadzo pasina chinokonzera.
• Kurasikirwa kwekunzwa kunogona kuita kuti vanhu vatadze kunyatsoona manzwiro ekubata, tembiricha, uye kurwadziwa munzvimbo dzakakanganiswa, izvo zvinogona kutungamirira kumhando dzakasiyana dzekukuvara.
• Kunyange zvazvo tsvakurudzo yakawedzerwa ichidiwa, mamwe matambudziko asina kuonekwa neuropathies angave ane zviduku zvefiber neuropathy zvinobatanidzwa.
• Imwe ongororo yakaratidza kuti neurogenic rosacea, mamiriro eganda, anogona kunge aine zvimwe zvinhu zvediki fiber neuropathy. (Min Li, et al., 2023)

Diki Nerve Fibers

• Kune marudzi akati wandei etsinga diki; maviri mudiki faibha neuropathy anosanganisira A-delta uye C. (Josef Finsterer, Fulvio A. Scorza. 2022)
• Aya madiki tsinga fiber akagoverwa mumuviri wese kusanganisira kumusoro kweminwe nezvigunwe, hunde, uye nhengo dzemukati.
• Fiber idzi dzinowanzowanikwa munzvimbo dzepamusoro dzemuviri, sepadyo nepamusoro peganda. (Mohammad A. Khoshnoodi, et al., 2016)
• Idzo tsinga diki dzetsinga dzinokuvara dzinobatanidzwa mukufambisa marwadzo uye tembiricha sensations.
• Tsinga zhinji dzine rudzi rwakakosha rwekusunga inonzi myelin inodzidzivirira uye inowedzera kumhanya kwetsinga.
• Mitsipa midiki inogona kunge iine sheath yakatetepa, ichiita kuti iwedzere kukuvara uye kukuvara panguva dzekutanga mamiriro uye zvirwere. (Heidrun H. Krämer, nevamwe, 2023)

Vanhu Panjodzi

Mhando dzakawanda dzeperipheral neuropathy dzinokonzera kukanganisa kune diki uye hombe peripheral nerve fibers. Nekuda kweizvi, mazhinji neuropathies musanganiswa wediki-fiber uye yakakura-fiber neuropathy. Zvinowanzoitika panjodzi dzekusanganiswa fiber neuropathy dzinosanganisira: (Stephen A. Johnson, nevamwe, 2021)

• chirwere cheshuga
• Kusakwana kwezvokudya
• Kunyanya kunwa doro
• Zvimwe zvinetso zvekudzivirira
• Mushonga toxicity

Isolated diki-fiber neuropathy haiwanzo, asi kune mamiriro anozivikanwa anobatsira kune chikonzero uye anosanganisira: (Stephen A. Johnson, nevamwe, 2021)

Sjogren Syndrome

• Iyi autoimmune disorder inokonzera kuoma kwemaziso nemuromo, matambudziko emazino, uye kurwadziwa kwemajoini.
• Inogonawo kukonzera kukuvara kwetsinga mumuviri wese.

Fabry Chirwere

• Ichi chiitiko chinokonzeresa kuunganidzwa kwemamwe mafuta / lipids mumuviri izvo zvinogona kutungamira kune neurological mhedzisiro.

Amyloidosis

• Ichi chirwere chisingawanzoitiki chinokonzera kuunganidzwa kwemapuroteni mumuviri.
• Mapuroteni anogona kukuvadza matishu semoyo kana tsinga.

Lewy Body Disease

• Ichi chirwere chetsinga chinokonzera dementia uye kusafamba zvakanaka uye chinogona kukonzera kukuvara kwetsinga.

Lupus

• Ichi chirwere che autoimmune chinokanganisa majoini, ganda, uye dzimwe nguva nerve tishu.

Utachiona hwehutachiona

• Zvirwere izvi zvinowanzokonzera kutonhora kana gastrointestinal / GI kugumbuka.
• Kashoma kazhinji vanogona kukonzera zvimwe zvinokonzeresa sediki fiber neuropathy.

Aya mamiriro akaonekwa achikonzeresa diki-fiber neuropathy kana kutanga sediki-fiber neuropathy isati yafambira mberi kune yakakura nerve fiber. Vanogonawo kutanga semusanganiswa weuropathy, nediki uye huru fiber.

Kufambira mberi

Kazhinji kukuvadzwa kunowedzera pamwero wepakati, zvichiita kuti uwedzere zviratidzo mukati memwedzi kana makore. Iyo fiber nerve inobatwa neiyo iri pasi pemamiriro anowanzo derera zvishoma nezvishoma, zvisinei kuti ari kupi. (Mohammad A. Khoshnoodi, et al., 2016) Mishonga inogona kubatsira kuderedza kukuvadza kune peripheral nerves. Kune vanhu vanoonekwa padanho rekutanga, zvinokwanisika kumisa kufambira mberi, uye zvinogona kudzivirira kubatanidzwa kwemafibhi makuru.

Mishonga

Kurapa kudzivirira kufambira mberi kunoda kudzora mamiriro ekurapa ari pasi nemaitiro ekurapa zvichienderana nechikonzero. Mishonga inogona kubatsira kudzivirira kufambira mberi inosanganisira:

• Kudzora shuga yeropa kune vanhu vane chirwere cheshuga.
• Nutritional supplementation kuitira kurapwa kwekushaya vhitamini.
• Kurega kunwa doro.
• Kudzivirirwa kwekudzivirira kwekudzivirira kwezvirwere zve autoimmune.
• Plasmapheresis - ropa rinotorwa uye plasma inorapwa uye inodzoserwa kana kuchinjana kuitira kurapwa kwezvirwere zve autoimmune.

Symptom Treatment

Vanhu vanogona kuwana kurapwa kwezviratidzo zvisingadzose kana kurapa mamiriro acho asi zvinogona kubatsira nekuzorora kwenguva pfupi. Symptomatic kurapwa inogona kusanganisira: (Josef Finsterer, Fulvio A. Scorza. 2022)

• Pain management inogona kusanganisira mishonga uye/kana topical analgesics.
• Physical therapy - kutambanudza, masaja, decompression, uye kugadzirisa kuti muviri ugare wakasununguka uye uchichinjika.
• Kugadziriswa kwekubatsira kuvandudza kurongeka, izvo zvinogona kukanganisa nekurasikirwa kwekunzwa.
• Mishonga yekubvisa zviratidzo zveGI.
• Kupfeka zvipfeko zvehunyanzvi senge neuropathy masokisi kubatsira nemarwadzo etsoka zviratidzo.

Kurapa uye kurapa kweuropathies kazhinji kunosanganisira chiremba wetsinga. Chiremba wetsinga anogona kupa mushonga wekubatsira kuderedza zviratidzo zvekurwadziwa uye kupa kupindira mune zvekurapa senge immunotherapy kana paine kunetsekana kuti autoimmune process inogona kunge iri chikonzero. Pamusoro pezvo, kurapwa kunogona kusanganisira kuchengetwa kwemushonga wepanyama uye chiremba wekudzoreredza kana timu yekurapa muviri kuti ipe matambara uye maekisesaizi kubatsira kusimbisa muviri uye kuchengetedza kufamba uye kuchinjika.

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Peripheral Neuropathy Ngano & Chokwadi

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References

Johnson, SA, Shouman, K., Shelly, S., Sandroni, P., Berini, SE, Dyck, PJB, Hoffman, EM, Mandrekar, J., Niu, Z., Lamb, CJ, Low, PA, Singer , W., Mauermann, ML, Mills, J., Dubey, D., Staff, NP, & Klein, CJ (2021). Diki Fiber Neuropathy Chiitiko, Kuwanda, Kukanganisa Kwenguva refu, uye Kuremara. Neurology, 97(22), e2236–e2247. doi.org/10.1212/WNL.0000000000012894

Finsterer, J., & Scorza, FA (2022). Diki fiber neuropathy. Acta neurologica Scandinavica, 145 (5), 493-503. doi.org/10.1111/ane.13591

Krämer, HH, Bücker, P., Jeibmann, A., Richter, H., Rosenbohm, A., Jeske, J., Baka, P., Geber, C., Wassenberg, M., Fangerau, T., Karst , U., Schänzer, A., & van Thriel, C. (2023). Gadolinium kusiyanisa vamiririri: dermal deposits uye zvinogona kuitika pane epidermal diki nerve fibers. Nyaya yeNeurology, 270 (8), 3981-3991. doi.org/10.1007/s00415-023-11740-z

Li, M., Tao, M., Zhang, Y., Pan, R., Gu, D., & Xu, Y. (2023). Neurogenic rosacea inogona kunge iri diki fiber neuropathy. Miganho mukutsvaga marwadzo (Lausanne, Switzerland), 4, 1122134. doi.org/10.3389/fpain.2023.1122134

Khoshnoodi, MA, Truelove, S., Burakgazi, A., Hoke, A., Mammen, AL, & Polydefkis, M. (2016). Longitudinal Assessment yeDiki Fiber Neuropathy: Uchapupu hweIsina-Length-Dependent Distal Axonopathy. JAMA neurology, 73 (6), 684-690. doi.org/10.1001/jamaneurol.2016.0057